PHA-767491 hydrochloride [Cas No. 942425-68-5]
Catalog No:TA-T6940
Manufacturer:TargetMol
Synonyms:CAY-10572 hydrochloride,PHA-767491 hydrochloride,PHA-767491,CAY10572
CAS No.:942425-68-5
Formula:C12H11N3O
MWt:213.24
€48,00 – €441,00
Name: | PHA767491 HCl |
Category: | Biochemicals |
Description: | PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1. |
Pathway: | PI3K/Akt/mTOR signaling,Cell Cycle/Checkpoint,GPCR/G Protein,Stem Cells |
Target: | CDK inhibitor,cholecystokinin inhibitor,GSK-3 inhibitor |
Receptor: | Cdk1, Cdk2, Cdk9, Cdc7, GSK-3β |
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