Mitoxantrone [Cas No. 65271-80-9]
Catalog No：TA-T6588
Manufacturer：TargetMol
Synonyms：mitozantrone
CAS No.：65271-80-9
Formula：C22H28N4O6
MWt：444.48
€35,00 – €122,00
| Name: | Mitoxantrone |
| Category: | Biochemicals |
| Description: | Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin. |
| Pathway: | DNA Damage/DNA Repair,Cytoskeletal Signaling |
| Target: | Topoisomerase inhibitor,PKC |
| Receptor: | Topo II,PKC |
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