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Western blot analysis of extracts of Mouse brain, using BCAR1 antibody (A18270) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Western blot analysis of extracts of HeLa cells, using BCAR1 antibody (A18270) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 180s.
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Immunohistochemistry of paraffin-embedded mouse kidney using BCAR1 Rabbit pAb (A18270) at dilution of 1:50 (40x lens).
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Immunohistochemistry of paraffin-embedded rat ovary using BCAR1 Rabbit pAb (A18270) at dilution of 1:50 (40x lens).
BCAR1 Rabbit pAb
Catalog No：AB-A18270
Manufacturer：ABclonal
Synonyms：BCAR1;CAS;CAS1;CASS1;CRKAS;P130Cas
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | BCAR1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. |
| Immunogen: | Recombinant protein of human BCAR1. |
| Gene ID: | 9564 |
| Swiss prot: | P56945 |
| Molecular weight: | 93kDa |
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