Western blot analysis of extracts of rat brain, using ATG4B antibody (A14112) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 60s.
ATG4B Rabbit pAb
Catalog No:AB-A14112
Manufacturer:ABclonal
Synonyms:ATG4B;APG4B;AUTL1
Applications:WB
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ATG4B Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human ATG4B (NP_037457.3). |
Gene ID: | 23192 |
Swiss prot: | Q9Y4P1 |
Molecular weight: | 31kDa/37kDa/42kDa/44kDa/52kDa |
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