WZ-3146 [Cas No. 1214265-56-1]
Catalog No：TA-T6733
Manufacturer：TargetMol
CAS No.：1214265-56-1
Formula：C24H25ClN6O2
MWt：464.95
€48,00 – €768,00
| Name: | WZ3146 |
| Category: | Biochemicals |
| Description: | WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM, does not inhibit ERBB2 phosphorylation (T798I). |
| Pathway: | Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors |
| Target: | EGFR inhibitor |
| Receptor: | EGFR (E746_A750), EGFR (E746_A750/T790M), EGFR (L858R), EGFR (L858R/T790M) |
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