Aspirin [Cas No. 50-78-2]
Catalog No:TA-T0005
Manufacturer:TargetMol
Synonyms:Acetylsalicylic Acid,ASA,Acetylsalicylate
CAS No.:50-78-2
Formula:C9H8O4
MWt:180.16
€28,00 – €87,00
Product Name: | Aspirin |
Category: | Biochemicals > Small Compounds |
Description: | Acetylsalicylic acid is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Acetylsalicylic acid is a histone deacetylase inhibitors to up-regulate cell cycle arrest protein p21, which can suppresses ovarian Y cells harboring COX-1. Acetylsalicylic acid also inhibits the expression of COX-2 in HUVEC and neonatal rat ventricular cardiomyocytes, and then reduce PG production and the down-regulation of ERK and NF-KB, respectively. |
Publications: | 1. Bi X, Yan X, Jiang B, et al. Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses. Toxicology and Applied Pharmacology. 2021: 115778. 2. Liu Z, Tan S, Zhou L, et al.SCGN deficiency is a risk factor for autism spectrum disorder.Signal Transduction and Targeted Therapy.2023, 8(1): 1-15. |
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