ASIP Rabbit pAb
Catalog No:AB-A6872
Manufacturer:ABclonal
Synonyms:ASIP;AGSW;AGTI;AGTIL;ASP;SHEP9
Applications:IHC,IF
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ASIP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-132 of human ASIP (NP_001663.2). |
Gene ID: | 434 |
Swiss prot: | P42127 |
Molecular weight: | 14kDa |
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