AZD1283 [Cas No. 919351-41-0]
Catalog No：TA-T3536
Manufacturer：TargetMol
CAS No.：919351-41-0
Formula：C23H26N4O5S
MWt：470.54
€31,00 – €1.270,00
| Name: | AZD1283 |
| Category: | Biochemicals |
| Description: | AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 μg/kg/min, respectively. The doses induced the increase in bleeding time at 33 and 100 μg/kg/min for 3- and 13-fold, respectively. Thus, the therapeutic index (TI) was ≥10 for both compounds. |
| Pathway: | Neuroscience |
| Target: | P2 Receptor inhibitor |
| Receptor: | P2Y12 |
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