ARRB2 Rabbit pAb
Catalog No:AB-A16764
Manufacturer:ABclonal
Synonyms:ARRB2;ARB2;ARR2;BARR2
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | ARRB2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ARRB2 (NP_004304.1). |
Gene ID: | 409 |
Swiss prot: | P32121 |
Molecular weight: | 44kDa/45kDa/46kDa/47kDa/48kDa |
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