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Western blot analysis of extracts of various cell lines, using ARRB1 antibody (A0998) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded rat heart using ARRB1 antibody (A0998) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using ARRB1 antibody (A0998) at dilution of 1:100 (40x lens).
ARRB1 Rabbit pAb
Catalog No：AB-A0998
Manufacturer：ABclonal
Synonyms：ARRB1;ARB1;ARR1
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ARRB1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 169-418 of human ARRB1 (NP_004032.2). |
| Gene ID: | 408 |
| Swiss prot: | P49407 |
| Molecular weight: | 46kDa/47kDa |
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