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Western blot analysis of extracts of various cell lines, using ARNT2 antibody (A8060) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human kidney using ARNT2 antibody (A8060) at dilution of 1:100 (40x lens).
ARNT2 Rabbit pAb
Catalog No：AB-A8060
Manufacturer：ABclonal
Synonyms：ARNT2;WEDAS;bHLHe1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ARNT2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-690 of human ARNT2 (NP_055677.3). |
| Gene ID: | 9915 |
| Swiss prot: | Q9HBZ2 |
| Molecular weight: | 77kDa/78kDa |
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