Arg- Glu(EDANS)- (Asn670,Leu671)-Amyloid b/A4Protein Precursor770 (668-675)- Lys(DABCYL)-Arg
Catalog No:CP-AMYD-045B
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:[310427-94-2]
Formula:C91H129 N25O25S 1
MWt:2,005
€208,00
Product Name: | Arg- Glu(EDANS)- (Asn670,Leu671)- Amyloid b/A4 Protein Precursor770 (668-675)- Lys(DABCYL)- Arg |
Category: | Peptides |
Three letter sequence: | Arg- Glu(EDANS)- Glu-Val-Asn- Leu-Asp-Ala- Glu-Phe- Lys(DABCYL )-Arg |
One letter sequence: | R-E(EDANS)- EVNLDAEF- K(DABCYL)-R |
Description: | Fluorogenic substrate for pro- memapsin-2 containing the 尾- secretase site of the Swedish mutation of APP. The kinetic parameters at pH 4.5 are Km = 5.4 碌M and kcat = 0.24 min-1. |
Literature References: | A.K. Ghosh et al., J. Amer. Chem. Soc ., 122, 3522 (2000); J. Ermolieff et al., Biochemistry, 39, 12450 (2000) |
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