Western blot analysis of extracts of various cell lines, using ARAP2 antibody (A12254) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
ARAP2 Rabbit pAb
Catalog No:AB-A12254
Manufacturer:ABclonal
Synonyms:ARAP2;CENTD1;PARX
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ARAP2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1405-1704 of human ARAP2 (NP_056045.2). |
Gene ID: | 116984 |
Swiss prot: | Q8WZ64 |
Molecular weight: | 193kDa |
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