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Western blot analysis of extracts of various cell lines, using APLP2 Polyclonal Antibody (A5455) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
APLP2 Rabbit pAb
Catalog No：AB-A5455
Manufacturer：ABclonal
Synonyms：APLP2;APLP-2;APPH;APPL2;CDEBP
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | APLP2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer’s disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-450 of human APLP2 (NP_001135750.1). |
| Gene ID: | 334 |
| Swiss prot: | Q06481 |
| Molecular weight: | 59kDa/79kDa/80kDa/85kDa/86kDa/87kDa |
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