(Z)-Semaxinib [Cas No. 194413-58-6]
Catalog No:TA-T2496
Manufacturer:TargetMol
Synonyms:SU5416
CAS No.:194413-58-6
Formula:C15H14N2O
MWt:238.28
€58,00 – €997,00
Name: | (Z)-Semaxinib |
Category: | Biochemicals |
Description: | Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. Semaxanib is a quinolone derivative with potential antineoplastic activity. |
Pathway: | Angiogenesis, Tyrosine Kinase/Adaptors |
Target: | VEGFR inhibitor |
Receptor: | VEGFR2/Flk1 |
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