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Western blot analysis of extracts of HeLa cells, using APC antibody (A2818) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human breast cancer using APC antibody (A2818) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded human colon using APC antibody (A2818) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded human lung using APC antibody (A2818) at dilution of 1:200 (40x lens).
APC Rabbit pAb
Catalog No：AB-A2818
Manufacturer：ABclonal
Synonyms：APC;BTPS2;DP2;DP2.5;DP3;GS;PPP1R46
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | APC Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2544-2843 of human APC (NP_000029.2). |
| Gene ID: | 324 |
| Swiss prot: | P25054 |
| Molecular weight: | 300kDa/311kDa |
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