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Western blot analysis of extracts of various cell lines, using APC antibody (A17912) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
APC Rabbit mAb
Catalog No：AB-A17912
Manufacturer：ABclonal
Synonyms：APC;BTPS2;DP2;DP2.5;DP3;GS;PPP1R46
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | APC Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human APC |
| Gene ID: | 324 |
| Swiss prot: | P25054 |
| Molecular weight: | 160kDa |
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