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Western blot analysis of extracts of various cell lines, using ANTXR1 antibody (A6525) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
ANTXR1 Rabbit pAb
Catalog No：AB-A6525
Manufacturer：ABclonal
Synonyms：ANTXR1;ATR;GAPO;TEM8
Applications：WB,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ANTXR1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 84-333 of human ANTXR1 (NP_060623.2). |
| Gene ID: | 84168 |
| Swiss prot: | Q9H6X2 |
| Molecular weight: | 33kDa/37kDa/39kDa/41kDa/59kDa/62kDa |
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