Western blot analysis of extracts of various cell lines, using ANGPT1 antibody (A15026) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
ANGPT1 Rabbit pAb
Catalog No:AB-A15026
Manufacturer:ABclonal
Synonyms:ANGPT1;AGP1;AGPT;ANG1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ANGPT1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-293 of human ANGPT1 (NP_001186788.1). |
Gene ID: | 284 |
Swiss prot: | Q15389 |
Molecular weight: | 57kDa |
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