Olmutinib [Cas No. 1353550-13-6]
Catalog No：TA-T6918
Manufacturer：TargetMol
Synonyms：HM61713, BI 1482694,BI 1482694,HM61713
CAS No.：1353550-13-6
Formula：C26H26N6O2S
MWt：486.59
€42,00 – €538,00
| Name: | Olmutinib |
| Category: | Biochemicals |
| Description: | Olmutinib is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form. |
| Pathway: | Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors |
| Target: | EGFR inhibitor,BTK |
| Receptor: | EGFR (cell: H1975), EGFR (cell: HCC827),BTK |
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