CDDO-dhTFEA [Cas No. 1191265-33-4]
Catalog No：TA-T13604
Manufacturer：TargetMol
Synonyms：RTA dh404
CAS No.：1191265-33-4
Formula：C33H45F3N2O3
MWt：574.72
€144,00 – €3.074,00
| Name: | CDDO-dhTFEA |
| Category: | Biochemicals |
| Description: | CDDO-dhTFEA is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. It restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats. |
| Pathway: | Immunology & Inflammation,NF-κB |
| Target: | NF-κB,Nrf2 |
| Receptor: | NF-κB,Nrf2 |
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