Triamcinolone [Cas No. 124-94-7]
Catalog No：TA-T0798
Manufacturer：TargetMol
Synonyms：Fluoxyprednisolone,Aristocort,Rodinolone
CAS No.：124-94-7
Formula：C21H27FO6
MWt：394.44
€30,00 – €100,00
| Name: | Triamcinolone |
| Category: | Biochemicals |
| Description: | Triamcinolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to translocation of the ligand-receptor complex to the nucleus and induces expression of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both mediators of inflammation. In addition, pro-inflammatory cytokine production, including interleukin (IL)-1and IL-6, and the activation of cytotoxic T-lymphocytes is also inhibited. T-cells are prevented from making IL-2 and proliferating. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis through increasing Ikappa-B expression and curtailing activation of nuclear factor (NF)kappa-B. |
| Pathway: | Immunology & Inflammation, Metabolism, Neuroscience |
| Target: | COX inhibitor, Glucocorticoid Receptor antagonist |
| Receptor: | COX, Glucocorticoid Receptor |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：TA-PDK0060
Manufacturer：TargetMol
CAS No.：135-97-7
Formula：C8H15NO
MWt：141.21
€50,00
Catalog No：TA-PDK0014
Manufacturer：TargetMol
CAS No.：1076-22-8
Formula：C6H6N4O2
MWt：166.1
€47,00 – €112,00
Catalog No：TA-Fr16745
Manufacturer：TargetMol
CAS No.：14191-95-8
Formula：C8H7NO
MWt：133.15
€42,00 – €50,00
Catalog No：TA-Fr16605
Manufacturer：TargetMol
CAS No.：486-70-4
Formula：C10H19NO
MWt：169.3
€50,00 – €1.980,00
Catalog No：TA-Fr12277
Manufacturer：TargetMol
CAS No.：13252-83-0
Formula：C10H8O3
MWt：176.1
€50,00 – €80,00
Catalog No：TA-T0020
Manufacturer：TargetMol
Synonyms：4-Amino-salicylic acid sodium salt,Sodium 4-Aminosalicylate
CAS No.：6018-19-5
Formula：C7H6NNaO3﹞2H2O
MWt：211.15
€16,00 – €75,00