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Western blot analysis of extracts of various cell lines, using AMACR antibody (A1130) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded human prostate cancer using AMACR Rabbit pAb (A1130) at dilution of 1:100 (40x lens).
AMACR Rabbit pAb
Catalog No：AB-A1130
Manufacturer：ABclonal
Synonyms：AMACR;AMACRD;CBAS4;P504S;RACE;RM
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | AMACR Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human AMACR (NP_976316.1). |
| Gene ID: | 23600 |
| Swiss prot: | Q9UHK6 |
| Molecular weight: | 22kDa/25kDa/42kDa/43kDa |
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