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Western blot analysis of extracts of various cell lines, using ALDH18A1 antibody (A12247) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
ALDH18A1 Rabbit pAb
Catalog No：AB-A12247
Manufacturer：ABclonal
Synonyms：ALDH18A1;ADCL3;ARCL3A;GSAS;P5CS;PYCS;SPG9;SPG9A;SPG9B
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ALDH18A1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ALDH18A1 (NP_002851.2). |
| Gene ID: | 5832 |
| Swiss prot: | P54886 |
| Molecular weight: | 87kDa |
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