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Western blot analysis of extracts of various cell lines, using AKTIP antibody (A6239) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 40s.
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Immunohistochemistry of paraffin-embedded rat brain using AKTIP antibody (A6239) at dilution of 1:100 (40x lens).
AKTIP Rabbit pAb
Catalog No：AB-A6239
Manufacturer：ABclonal
Synonyms：AKTIP;FT1;FTS
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | AKTIP Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB’s regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human AKTIP (NP_071921.1). |
| Gene ID: | 64400 |
| Swiss prot: | Q9H8T0 |
| Molecular weight: | 33kDa |
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