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Western blot analysis of extracts of various cell lines, using AIRE antibody (A14183) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
AIRE Rabbit pAb
Catalog No：AB-A14183
Manufacturer：ABclonal
Synonyms：AIRE;AIRE1;APECED;APS1;APSI;PGA1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | AIRE Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human AIRE (NP_000374.1). |
| Gene ID: | 326 |
| Swiss prot: | O43918 |
| Molecular weight: | 25kDa/35kDa/36kDa/57kDa |
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