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Western blot analysis of extracts of various cell lines, using AGA antibody (A13942) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
AGA Rabbit pAb
Catalog No：AB-A13942
Manufacturer：ABclonal
Synonyms：AGA;AGU;ASRG;GA
Applications：WB,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | AGA Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-346 of human AGA (NP_000018.2). |
| Gene ID: | 175 |
| Swiss prot: | P20933 |
| Molecular weight: | 37kDa |
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