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Western blot analysis of extracts of various cell lines, using ADRA1B antibody (A7872) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
ADRA1B Rabbit pAb
Catalog No：AB-A7872
Manufacturer：ABclonal
Synonyms：ADRA1B;ADRA1;ALPHA1BAR
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ADRA1B Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. |
| Immunogen: | A synthetic peptide of human ADRA1B |
| Gene ID: | 147 |
| Swiss prot: | P35368 |
| Molecular weight: | 56kDa |
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