ADD3 Rabbit pAb
Catalog No：AB-A18336
Manufacturer：ABclonal
Synonyms：ADDL;CPSQ3;ADD3
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €325,00
| Product Name: | ADD3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ADD3 (NP_001307523.1). |
| Gene ID: | 120 |
| Swiss prot: | Q9UEY8 |
| Molecular weight: |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-A0082
Manufacturer：ABclonal
Synonyms：FGFR1;BFGFR;CD331;CEK;ECCL;FGFBR;FGFR-1;FLG;FLT-2;FLT2;HBGFR;HH2;HRTFDS;KAL2;N-SAM;OGD;bFGF-R-1
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0068
Manufacturer：ABclonal
Synonyms：BCR;ALL;BCR1;CML;D22S11;D22S662;PHL
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0059
Manufacturer：ABclonal
Synonyms：BSCL3;CGL3;LCCNS;MSTP085;PPH3;VIP21;CAV1
Applications：IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0066
Manufacturer：ABclonal
Synonyms：KAT2B;CAF;P/CAF;PCAF
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0038
Manufacturer：ABclonal
Synonyms：BRAF;B-RAF1;B-raf;BRAF1;NS7;RAFB1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0013
Manufacturer：ABclonal
Synonyms：CK-4, CK4, CYK4, K4, WSN1
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00