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Western blot analysis of extracts of various cell lines, using ACTN1 antibody (A1160) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded human liver cancer using ACTN1 antibody (A1160) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophagus using ACTN1 antibody (A1160) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using ACTN1 antibody (A1160) at dilution of 1:100 (40x lens).
ACTN1 Rabbit pAb
Catalog No：AB-A1160
Manufacturer：ABclonal
Synonyms：ACTN1;BDPLT15
Applications：WB,IHC
Reactivity：Human,Mouse,Monkey
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ACTN1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human ACTN1 (NP_001123477.1). |
| Gene ID: | 87 |
| Swiss prot: | P12814 |
| Molecular weight: | 102kDa/103kDa/105kDa/107kDa |
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