Acetyl-STAT3-K685 Rabbit pAb
Catalog No:AB-A20364
Manufacturer:ABclonal
Synonyms:APRF; HIES; ADMIO; ADMIO1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€150,00 – €410,00
Product Name: | Acetyl-STAT3-K685 Rabbit pAb |
Category: | Acetylated Antibodies |
Description: | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. |
Immunogen: | A synthetic acetylated peptide around K685 of human Acetyl-STAT3-K685. |
Gene ID: | 6774 |
Swiss prot: | P40763 |
Molecular weight: | 88kDa |
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