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Western blot analysis of extracts of various cell lines, using ACD antibody (A12177) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
ACD Rabbit pAb
Catalog No：AB-A12177
Manufacturer：ABclonal
Synonyms：ACD;PIP1;PTOP;TINT1;TPP1
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ACD Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACD (NP_001075955.1). |
| Gene ID: | 65057 |
| Swiss prot: | Q96AP0 |
| Molecular weight: | 57kDa |
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