Western blot analysis of extracts of Mouse heart, using ABCA1 antibody (A7228) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
ABCA1 Rabbit pAb
Catalog No:AB-A7228
Manufacturer:ABclonal
Synonyms:ABCA1;ABC-1;ABC1;CERP;HDLDT1;TGD
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ABCA1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier’s disease and familial high-density lipoprotein deficiency. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1870-2120 of human ABCA1 (NP_005493.2). |
Gene ID: | 19 |
Swiss prot: | O95477 |
Molecular weight: | 254kDa |
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