Western blot analysis of extracts of various cell lines, using 67kDa Laminin Receptor antibody (A9008) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
67kDa Laminin Receptor Rabbit pAb
Catalog No:AB-A9008
Manufacturer:ABclonal
Synonyms:RPSA;37LRP;67LR;ICAS;LAMBR;LAMR1;LBP;LBP/p40;LRP;LRP/LR;NEM/1CHD4;SA;lamR;p40
Applications:WB,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | 67kDa Laminin Receptor Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human 67kDa Laminin Receptor (NP_002286.2). |
Gene ID: | 3921 |
Swiss prot: | P08865 |
Molecular weight: | 32kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A0227
Manufacturer:ABclonal
Synonyms:MAPK14;CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;PRKM14;PRKM15;RK;SAPK2A;p38;p38ALPHA;p38 MAPK
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0185
Manufacturer:ABclonal
Synonyms:GDF15;GDF-15;MIC-1;MIC1;NAG-1;PDF;PLAB;PTGFB
Applications:WB,IHC,IF,IP
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0152
Manufacturer:ABclonal
Synonyms:TNNI3;CMD1FF;CMD2A;CMH7;RCM1;TNNC1;cTnI;troponin I3
Applications:WB,IF
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0082
Manufacturer:ABclonal
Synonyms:FGFR1;BFGFR;CD331;CEK;ECCL;FGFBR;FGFR-1;FLG;FLT-2;FLT2;HBGFR;HH2;HRTFDS;KAL2;N-SAM;OGD;bFGF-R-1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0062
Manufacturer:ABclonal
Synonyms:CYP1A2;CP12;P3-450;P450(PA);CYPIA2
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0024
Manufacturer:ABclonal
Synonyms:FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;PTK2
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €295,00