Western blot analysis of extracts of various cell lines, using 14-3-3 epsilon Rabbit mAb (A4933) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
14-3-3 epsilon Rabbit mAb
Catalog No:AB-A4933
Manufacturer:ABclonal
Synonyms:14-3-3E, HEL2, KCIP-1, MDCR, MDS
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | 14-3-3 epsilon Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008] |
Immunogen: | A synthesized peptide derived from human 14-3-3 epsilon |
Gene ID: | 7531 |
Swiss prot: | P62258 |
Molecular weight: | 29kDa |
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