BMS-1001 hydrochloride [Cas No. 2113650-04-5]
Catalog No：TA-T10565
Manufacturer：TargetMol
CAS No.：2113650-04-5
Formula：C35H35ClN2O7
MWt：631.11
€72,00 – €2.124,00
| Name: | BMS-1001 hydrochloride |
| Category: | Biochemicals |
| Description: | BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes. |
| Pathway: | Apoptosis, Cell Cycle/Checkpoint, Immunology & Inflammation |
| Target: | PD-1/PD-L1 |
| Receptor: | PD-1/PD-L1 |
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