Groenlandicine [Cas No. 38691-95-1]
Catalog No:TA-TN1037
Manufacturer:TargetMol
CAS No.:38691-95-1
Formula:C19H16NO4
MWt:322.33
€200,00 – €3.605,00
Name: | Groenlandicine |
Category: | Biochemicals |
Description: | Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage,Groenlandicine may be a promising anti-Alzheimer’s disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO(-) scavenging and good ROS inhibitory capacities. |
Pathway: | DNA Damage/DNA Repair |
Target: | Topoisomerase |
Receptor: | topoisomerase I |
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