ω-Conotoxin MVIIA
Catalog No：CP-TOXI-002
Manufacturer：CPC Scientific
Size：0.5 mg
CAS No.：107452-89-1
Formula：C102H172 N36O32S 7
MWt：2,639
€388,00
| Product Name: | ω-Conotoxin MVIIA |
| Category: | Peptides |
| Three letter sequence: | Cys-Lys-Gly- Lys-Gly-Ala- Lys-Cys-Ser- Arg-Leu-Met- Tyr-Asp-Cys- Cys-Thr-Gly- Ser-Cys-Arg- Ser-Gly-Lys- Cys-NH2 (Disulfide bridge: 1-16, 8-20, and 15- 25) |
| One letter sequence: | CKGKGAKCSR LMYDCCTGSC RSGKC-NH2 (Disulfide bridge: 1-16, 8- 20, and 15-25) |
| Description: | Reversible N-type Ca2+ Channel Blocker W-Conotoxin MVIIA, originally isolated from the venom of the fish-hunting cone snail Conus magus, is a blocker of voltage-sensitve Ca2+ channels in neurons. It has been used to identify different Ca2+ channel subtypes in amphibian brain. |
| Literature References: | Olivera, BM. et al. Biochem. 26, 2086 (1987); Hillyard, DR. et al. Neuron. 9, 69 (1992). B.M. Olivera, L.J. Cruz, V. de Santos, G.W. Le Cheminant, D. Griffin, R. Zeikus, J.M. McIntosh, R. Galyean, J. Varga, W.R. Gray, and J. Rivier, Biochemistry, 26, 2086 (1987). (Original) K. Valentino, R. Newcomb, T. Gadbois, T. Singh, S. Bowersox, S. Binter, A. Justice, D. Yamashiro, B.B. Hoffman, R. Ciaranello, G. Miljanich, and J. Ramachandran, |
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