ω-Conotoxin GVIA
Catalog No：CP-TOXI-001
Manufacturer：CPC Scientific
Size：1 mg
CAS No.：106375-28-4
Formula：C120H182 N38O43S 6
MWt：3,037
€423,00
| Product Name: | ω-Conotoxin GVIA |
| Category: | Peptides |
| Three letter sequence: | Cys-Lys-Ser- Hyp-Gly-Ser- Ser-Cys-Ser- Hyp-Thr-Ser- Tyr-Asn-Cys- Cys-Arg-Ser- Cys-Asn- Hyp-Tyr-Thr- Lys-Arg-Cys- Tyr-NH2 (Disulfide bridges: 1- 16, 8-19, 15- 26) |
| One letter sequence: | CKS(Hyp)GSSC S(Hyp)TSYNCC RSCN(Hyp)YTK RCY-NH2 |
| Description: | This peptide is a neurotoxin that blocks N-type calcium channels. N-type Ca2+ Channel Blocker |
| Literature References: | Rivier, J. et al. J. Biol. Chem. 262, 1194 (1987); Lampe, RA. et al. Biochem. 32, 3255 (1993); Wright, C. and JA. Angus, J. Cardiovasc. Pharmacol. 30, 392 (1997); Serone, A. and JA. Angus, Br. J. Pharmacol. 127, 927 (1999). B.M. Olivera, J.M. Mclntosh, L.J. Cruz, F.A. Luque, and W.R. Gray, Biochemistry, 23, 5087 (1984). (Original) Y. Nishiuchi, K. Kumagaye, Y. Noda, T.X. Watanabe, and S. Sakakibara, Biopolymers, 25, |
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