Western blot analysis of extracts of U-87MG cells, using SPRTN antibody (A11620) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
SPRTN Rabbit pAb
Catalog No:AB-A11620
Manufacturer:ABclonal
Synonyms:SPRTN;C1orf124;DVC1;PRO4323;spartan
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | SPRTN Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human SPRTN (NP_001010984.1). |
Gene ID: | 83932 |
Swiss prot: | Q9H040 |
Molecular weight: | 24kDa/29kDa/55kDa |
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