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Western blot analysis of extracts of various cell lines, using GRM1 antibody (A11462) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
GRM1 Rabbit pAb
Catalog No：AB-A11462
Manufacturer：ABclonal
Synonyms：GRM1;GPRC1A;MGLU1;MGLUR1;PPP1R85;SCAR13
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | GRM1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 920-1140 of human GRM1 (NP_000829.2). |
| Gene ID: | 2911 |
| Swiss prot: | Q13255 |
| Molecular weight: | 101kDa/132kDa |
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