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Immunohistochemistry of paraffin-embedded mouse liver using c-Myc antibody (A11394) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat heart using c-Myc antibody (A11394) at dilution of 1:100 (40x lens).
c-Myc Rabbit pAb
Catalog No：AB-A11394
Manufacturer：ABclonal
Synonyms：MRTL;MYCC;bHLHe39;c-Myc;MYC
Applications：IHC
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | c-Myc Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt’s lymphomas, suggesting its importance in the normal function of this gene. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350 to the C-terminus of human c-Myc (NP_002458.2). |
| Gene ID: | 4609 |
| Swiss prot: | P01106 |
| Molecular weight: | 48kDa/50kDa |
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