Western blot analysis of extracts of various cell lines, using ERp57 antibody (A1085) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
ERp57 Rabbit pAb
Catalog No:AB-A1085
Manufacturer:ABclonal
Synonyms:PDIA3;ER60;ERp57;ERp60;ERp61;GRP57;GRP58;HEL-S-269;HEL-S-93n;HsT17083;P58;PI-PLC
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ERp57 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 206-505 of human ERp57 (NP_005304.3). |
Gene ID: | 2923 |
Swiss prot: | P30101 |
Molecular weight: | 56kDa |
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