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Western blot analysis of extracts of various cell lines, using SDHB antibody (A10821) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded human colon using SDHB antibody (A10821) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using SDHB antibody (A10821) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat spleen using SDHB antibody (A10821) at dilution of 1:100 (40x lens).
SDHB Rabbit pAb
Catalog No：AB-A10821
Manufacturer：ABclonal
Synonyms：SDHB;CWS2;IP;PGL4;SDH;SDH1;SDH2;SDHIP
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SDHB Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-280 of human SDHB (NP_002991.2). |
| Gene ID: | 6390 |
| Swiss prot: | P21912 |
| Molecular weight: | 31kDa |
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