Phospho-PERK-T982 Rabbit pAb
Catalog No：AB-AP1243
Manufacturer：ABclonal
Synonyms：EIF2AK3;PEK;PERK;WRS
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-PERK-T982 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding T982 of human PERK. |
| Gene ID: | 9451 |
| Swiss prot: | Q9NZJ5 |
| Molecular weight: | 125kDa |
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