Phospho-NRAS-S89 Rabbit pAb
Catalog No:AB-AP1169
Manufacturer:ABclonal
Synonyms:NRAS; ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6; GTPase NRas
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€110,00 – €410,00
Product Name: | Phospho-NRAS-S89 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S89 of human NPhospho-NRAS-S89. |
Gene ID: | 4893 |
Swiss prot: | P01111 |
Molecular weight: | 21kDa |
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