Phospho-RB-S807 Rabbit mAb
Catalog No：AB-AP1135
Manufacturer：ABclonal
Synonyms：OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €325,00
| Product Name: | Phospho-RB-S807 Rabbit mAb |
| Category: | Phosphorylated Antibodies |
| Description: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S807 of human RB |
| Gene ID: | 5925 |
| Swiss prot: | P06400 |
| Molecular weight: | 106kDa |
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