Phospho-FAK-Y576/577 Rabbit pAb
Catalog No:AB-AP1098
Manufacturer:ABclonal
Synonyms:FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;PTK2
Applications:WB
Reactivity:Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-FAK-Y576/577 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015] |
Immunogen: | A phospho specific peptide corresponding to residues surrounding Y576/577 of human PTK2. |
Gene ID: | 5747 |
Swiss prot: | Q05397 |
Molecular weight: | 39kDa/48kDa/63kDa/99kDa/114kDa/119kDa/120kDa |
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