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Western blot analysis of extracts of various cell lines, using Phospho-ɑ-Synuclein-Y133 pAb (AP1093) at 1:1000 dilution.Jurkat and NIH/3T3 cells were treated by Pervanadate (1 mM) at 37℃ for 30 minutes.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
Phospho-α-Synuclein-Y133 Rabbit pAb
Catalog No：AB-AP1093
Manufacturer：ABclonal
Synonyms：PD1;NACP;PARK1;PARK4;SNCA
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-伪-Synuclein-Y133 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer’s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y133 of human alpha-Synuclein. |
| Gene ID: | 6622 |
| Swiss prot: | P37840 |
| Molecular weight: | 14kDa |
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