Phospho-Histone H2A-S129 Rabbit pAb
Catalog No:AB-AP1063
Manufacturer:ABclonal
Synonyms:H2A1;SPT11
Applications:IHC
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-Histone H2A-S129 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A. |
Gene ID: | 851811 |
Swiss prot: | P04911 |
Molecular weight: | 14kDa |
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